Boston is set open the 2016 regular reason today in Cleveland against the Indians. The Red Sox, who followed the 2013 championship season with two straight last place finishes in the American League East, will be managed for a fourth year by John Farrell, who returns to the helm after undergoing treatment for lymphoma that caused him to miss several games at the end of last season. Boston will play an additional road series in Toronto against the Blue Jays before opening Fenway Park next Monday versus the Baltimore Orioles.

Many familiar faces return from last season; besides Ortiz, the roster features newly minted first baseman Hanley Ramirez, second baseman Dustin Pedroia, shortstop Xander Bogaerts, outfielder Mookie Betts, and starting pitchers Clay Buchholz, Joe Kelly, and Rick Porcello. Another familiar face who returns as a starter this season is infielder Brock Holt, who was the lone representative for Boston at last year’s All Star Game.

Some of the new faces are already familiar to Boston fans. Pitcher David Price, who faced the Red Sox several times as a Tampa Bay starting pitcher, joins the club with the richest contract ever given in franchise history (seven years, $217 million). Chris Young, formally with the Yankees, begins the season as a reserve outfielder. One player less familiar to fans but prepared to make an impact is Craig Kimbrel, who signed as a free agent after six years split between the Braves and the Padres; he takes over the closer spot from Koji Uehara, who becomes Boston’s newest set up man.

Here is the complete Opening Day roster for Boston:

Pitchers (12)
David Price, Clay Buchholz, Joe Kelly, Rick Porcello, Steven Wright, Matt Barnes, Craig Kimbrel, Tommy Layne, Noe Ramirez, Robbie Ross Jr., Junichi Tazawa, and Koji Uehara

Catchers (2)
Ryan Hanigan and Blake Swihart

Infielders (6)
Xander Bogaerts, Brock Holt, Dustin Pedroia, Hanley Ramirez, Pablo Sandoval, and Travis Shaw

Outfielders (4)
Mookie Betts, Jackie Bradley Jr., Rusney Castillo, and Chris Young

Designated Hitter (1)
David Ortiz

Starting pitchers Eduardo Rodriguez and Brandon Workman, relief pitcher Carson Smith, and catcher Christian Vazquez will begin the season on the 15-day disabled list.

The Boston Red Sox, a season removed from a world championship, are set to open the 2015 regular reason today in Philadelphia against the Phillies, the first time in team history that Boston will open against a National League opponent. The Red Sox, who followed the 2013 championship season with a last place finish in the American League East, the second such finish in three seasons, will be managed for a third year by John Farrell. Boston will play an additional road series in New York against the Yankees before opening Fenway Park next Monday versus the Washington Nationals.

Many familiar faces return from last season, including designated hitter David Ortiz, who will start the opener at Citizens Bank Park as the first baseman, first baseman Mike Napoli, second baseman Dustin Pedroia, shortstop Xander Bogaerts, outfielder Shane Victorino, and starting pitcher Clay Buchholz. Another familiar face who returns as a starter this season is outfielder Mookie Betts, who will likely play his first full season at the major league level and has already drawn interest as a dark horse MVP candidate.

Some of the new faces are already familiar to fans of the Boston nine. Outfielder Hanley Ramirez, who came up through the Red Sox farm system as a shortstop and appeared in two games with Boston before being part of a trade in November 2005 for Josh Beckett and Mike Lowell, returns to the fold, as does starting pitcher Justin Masterson, who appeared in 67 games for Boston in 2008 and 2009. Other new players include third baseman Pablo Sandoval, who played for seven seasons in San Francisco and won three World Series with the Giants, including last season, and pitcher Rick Porcello, who came as part of a trade with Detroit for Yoenis Cespedes.

Here is the complete Opening Day roster for Boston:

Pitchers (12)
Clay Buchholz, Rick Porcello, Justin Masterson, Wade Miley, Edward Mujica, Junichi Tazawa, Anthony Varvaro, Alexi Ogando, Craig Breslow, Robbie Ross Jr., Steven Wright, and Tommy Layne

Catchers (2)
Ryan Hanigan and Sandy Leon

Infielders (5)
Mike Napoli, Dustin Pedroia, Xander Bogaerts, Pablo Sandoval, and Brock Holt

Outfielders (5)
Hanley Ramirez, Mookie Betts, Shane Victorino, Daniel Nava, and Allen Craig

Designated Hitter (1)
David Ortiz

Closer Koji Uehara, starting pitcher Joe Kelly, and relief pitcher Edwin Escobar will begin the season on the 15-day disabled list. Catcher Christian Vazquez, who had Tommy John surgery on his right elbow last week, will miss the entire 2015 season.